AbCellera is a young, energetic, and rapidly growing technology company with an amazing team that searches, decodes, and analyzes natural immune systems to find antibodies that its partners can develop into drugs to prevent and treat disease. With nearly 400 AbCellerites and growing, we’re expanding our capabilities to include internal CMC development and GMP manufacturing of antibodies to bring therapies from idea to patients, faster.
We are seeking a highly motivated Associate Scientist to join the Analytical Operations team within CMC at AbCellera. In this capacity, the Associate Scientist will be responsible for assisting in establishing platform analytical methods for use across the analytical function in Process Development.
The successful candidate will help to establish both highly resolving methods to support QC lot release as well as high throughput methods to support process development activities. This is an exciting opportunity for a candidate with a solid foundation in separation science, primarily chromatographic and electrophoretic techniques.
How you might spend your days:
- Supporting analytical method development, qualification, and transfer across a range of technologies (LC, CE, UV-Vis, etc)
- Developing new analytical methods in support of release testing and product characterization
- Performing routine analyses of samples in support of monoclonal antibody process development
- Generating high quality data and technical reports in support of method development, qualification, and product characterization
- Aggregating and presenting analytical data to stakeholders within Analytical Development and across the CMC organization
- Contributing to CMC technical teams in the form of analytical investigation support, data generation, interpretation, and presentation
- Collaborating with our Research organization to drive harmony in analytical methodology and technology
- Researching and evaluating technological advances in the field of analytical chemistry
- Connecting scientific experimental design and execution to key business objectives
- Applying AQbD principles to analytical method development
We'd love to hear from you if you have:
- A BSc degree in Analytical Chemistry, Biochemistry or related discipline with 5+ years experience or an MSc with 2-4 years of experience
- Experience working in areas of therapeutic protein characterization in either academia or biotechnology
- Strong data and time organization/management skills; proficiency in multi-tasking
- Technical proficiency in separation based analytical method development and qualification including SEC, IEX, RP, HILIC, CE-SDS, SEC-MALS/QELS, and icIEF methods
- Proficiency working with data acquisition platforms such as Empower, Compass, 32Karat, etc
- Familiarity with electronic lab notebooks (Ex. Benchling), experimental data capture, and the associated 21 CFR part 11 compliance requirements
- Demonstrated ability to learn, understand and master new experimental techniques
- Experience with CMC analytical development of monoclonal antibodies or related biotherapeutic proteins is a plus
- Knowledge of regulatory filings such as INDs, BLAs, IMPDs, etc would be advantageous.
- Provent yourself to be a problem-solver and team player with strong written and verbal communication skills
- Familiarity with regulatory requirements as it pertains to CMC activities for monoclonal antibodies (FDA, EMA, ICH, etc)
What we offer:
A generous compensation package including an equity stake in AbCellera’s success. Our headquarters are nestled in the heart of Vancouver, Canada - we’ll support you and your family in every way we can to relocate if you haven't had the joy of living in this beautiful area!
About AbCellera:
At AbCellera, we’re solving tough problems and creating innovative solutions from the ground up - custom immunizations, microfluidics, high-throughput imaging, genomics, computation, machine learning and laboratory automation. We’re revolutionizing how our scientists can explore antibodies and the scale at which they can do so. This is life-changing research and you could be a part of it.
You’ll join a diverse and multi-disciplinary team of biologists, biochemists, engineers, bioinformaticians, computer scientists and physicists - all working together to bring better therapies to patients. We’re a growing company with a high-throughput pipeline and the drive to be the best in the industry. This isn’t just about having the best technology. We know we need a world-class team of visionaries and innovators. We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success. We’re looking for someone like you to help us get there.
To apply:
Please send us your application through our website and refer to Job ID 220054 in your cover letter. We apologize in advance, but we receive a large volume of applications, and will only contact those who are selected for an interview.