Identifying T-cell engagers with optimal potency and cytokine-release profiles with a diverse panel of CD3-binding antibodies

Mai M, et al. American Association for Cancer Research^® (AACR) Annual Meeting, April 2023

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This poster provides a comprehensive data package on a panel of novel, fully human CD3-binding antibodies, including binding and functional comparisons to molecules commonly used for T-cell engager (TCE) development. Proof-of-concept data illustrates how these antibodies could enable the development of optimal TCEs for different tumor targets.

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